Many centuries ago, Dr. Parnassus won immortality in a bet that found the malevolent Mr. Nick coming up short. While few would be foolish enough to try their luck against the powers of darkness a second time, Dr. Parnassus did precisely that -- this time trading his mortality for youth on the understanding that his firstborn would become the property of Mr. Nick when the child reaches his or her 16th birthday.Flash-forward to the present day, and Dr. Parnassus' daughter, Valentina, is about to celebrate her sweet sixteen. Dr. Parnassus is desperate to save his little girl from her fiery fate, so when Mr. Nick arrives to collect, he senses the good doctor's malaise and cooks up a wager too enticing to refuse: Dr. Parnassus and Mr. Nick will each compete to seduce five souls, with possession of Valentina going to whoever manages to complete the task first. As the competition begins to heat up, a mysterious man named Tony appears. Could Tony be the one man capable of helping Dr. Parnassus win the competition and save Valentina?